I am using the strikethrough feature in Print Shop Mail but I want the color of the strikethrough line to be different from the text that it is striking through. Is there any way to do that?

That's not really supported but maybe this is close enough:

1. Duplicate the text object.
2. Make sure the copy is at the exact same position as the original object.
3. In the object at the back, set the style to strikethrough and the color to (for example) red.
4. In the object at the front, set style and color to normal (no strikethrough, black).